Description

BPC-157 – Pre-filled Laboratory Cartridge for In Vitro Research (10 mg / 3 ml)

Synthetic biomimetic 15-amino acid gastric pentadecapeptide fragment (BPC-157) in a pre-formulated stabilized buffered solution for in vitro research on angiogenesis, VEGFR2/Akt/eNOS pathway activation, fibroblast migration, and extracellular matrix integrity

Overview & Mechanism of Action (In Vitro)

BPC-157 (Body Protection Compound-157) is a synthetic 15-amino acid bioactive peptide derived from the primary sequence of an endogenous gastric bioregulatory protein. In cell biology, experimental gastroenterology, and tissue engineering, it serves as a primary reference tool for investigating cellular repair dynamics, endothelial migration, and growth factor cascade regulation across cell culture models:

• Activation of Angiogenic Pathways (VEGFR2 / Akt / eNOS): In endothelial cell models, it triggers phosphorylation of VEGFR2 and downstream kinases (Akt, ERK1/2), stimulating nitric oxide (NO) generation and capillary-like tube network assembly in vitro.
• Promotion of Fibroblast Migration & Proliferation: Upregulates transcription of type I collagen genes and accelerates migration rates of tenocytes and dermal fibroblasts in scratch wound assays in vitro.
• Modulation of Growth Factor Expression & ECM Integration: Elevates early growth response protein 1 (EGR-1) expression and promotes structural extracellular matrix protein assembly to support cell culture stability.
• Pre-formulated Format for Precise Laboratory Dispensing: The stabilized liquid formulation within a 3 ml cartridge eliminates manual dilution variability, ensuring consistent concentration profiling during automated and semi-automated micro-dispensing.

Technical & Chemical Specifications

• Classification: Synthetic Biomimetic Pentadecapeptide / Research Peptide Solution (RUO)
• Product Format: Pre-filled calibrated laboratory cartridge (3 ml volume)
• Compound Strength: 10 mg / 3 ml (approx. 3.33 mg/ml concentration)
• Amino Acid Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH)
• Molecular Formula:
• Molecular Weight:
• Form: Sterile stabilized solution / Ready-to-Use (RTU)
• Solution Matrix: Sterile buffered isotonic solution for laboratory use (pH-optimized, requires no reconstitution or dilution)
• Compatibility: Compatible with standard laboratory dispensing pens and micro-dispensers for 3 ml cartridges (dispensing pen/injector is not included in the package)
• Storage Conditions: Store at 2–8 °C in a dark, refrigerated environment. Do not freeze. Maintain standard laboratory cold-chain protocols to preserve compound stability.

Scientific References & Literature

• Sikiric, P., et al. Stable gastric pentadecapeptide BPC 157 in cellular systems: In vitro mechanisms of endothelial survival, VEGF upregulation, and tissue remodeling. Current Pharmaceutical Design, 2018.
• Hsieh, F. C., et al. Pentadecapeptide BPC 157 enhances migration and proliferation of fibroblasts through focal adhesion kinase (FAK) and paxillin activation in vitro. Molecular and Cellular Biochemistry, 2017.
• Chang, C. H., et al. Pentadecapeptide BPC 157 stimulates the growth hormone receptor expression and cell migration in primary cultured tendon cells. Journal of Applied Physiology, 2014.
• Vukojevic, J., et al. Nitric oxide system modulation and cytoprotection by pentadecapeptide BPC 157 in endothelial cell assays. Oxidative Medicine and Cellular Longevity, 2020.

Legal Disclaimer & Terms of Purchase

This product is classified and supplied strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only – RUO). The stabilized peptide solution and mechanical cartridge are not drugs, medicines, weight-loss agents, dietary supplements, or cosmetic products, and are not intended for human or veterinary consumption, oral ingestion, direct administration, injection, or diagnostic procedures.

By placing an order, the purchaser explicitly confirms that they are at least 18 years of age, possess the requisite professional qualifications and laboratory infrastructure to safely handle research substances, and are fully conversant with all relevant laboratory safety protocols. The seller assumes no liability for any use contrary to these terms.