{"id":1888,"date":"2026-09-11T08:15:52","date_gmt":"2026-09-11T08:15:52","guid":{"rendered":"https:\/\/nextrabiochem.eu\/produkt\/glow-70mg-2\/"},"modified":"2026-09-11T12:16:05","modified_gmt":"2026-09-11T12:16:05","slug":"glow-70mg-2","status":"publish","type":"product","link":"https:\/\/nextrabiochem.eu\/en\/produkt\/glow-70mg-2\/","title":{"rendered":"GLOW 70mg"},"content":{"rendered":"<p><strong>GLOW<\/strong><\/p>\n<p><i>Synthetic multi-peptide research complex (BPC-157 + TB-500 + GHK-Cu) for in vitro research on cell migration, angiogenesis, and extracellular matrix remodeling<\/i><\/p>\n<p><strong>Overview &amp; Mechanism of Action (In Vitro)<\/strong><\/p>\n<p><strong>GLOW<\/strong> is a specialized multi-component laboratory blend combining three complementary research peptides: the pentadecapeptide <strong>BPC-157<\/strong>, the synthetic thymosin \u03b24 fragment (<strong>TB-500<\/strong>), and the copper tripeptide chelate (<strong>GHK-Cu<\/strong>). In molecular and cellular biology, it serves as a synergistic model for investigating intercellular signaling, tissue regeneration, and structural remodeling:<\/p>\n<ul>\n<li><strong>Cellular Migration &amp; Actin Cytoskeletal Dynamics (TB-500):<\/strong> Sequestration of monomeric G-actin and regulation of actin polymerization, facilitating the study of directed cell migration in endothelial cells, keratinocytes, and fibroblasts.<\/li>\n<li><strong>Modulation of Angiogenic &amp; Growth Pathways (BPC-157):<\/strong> Monitoring VEGFR2 (vascular endothelial growth factor receptor 2) signaling activation, stimulation of eNOS expression, and downregulation of pro-inflammatory mediators in endothelial models.<\/li>\n<li><strong>Extracellular Matrix Synthesis &amp; Gene Expression (GHK-Cu):<\/strong> Stimulation of type I and III collagen, elastin, and glycosaminoglycan (GAG) production in cultured dermal fibroblasts, alongside the modulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs).<\/li>\n<\/ul>\n<p>The combination of these three compounds in experimental cultures allows the evaluation of complex cellular repair cascades and tissue matrix turnover within a single assay system.<\/p>\n<p><strong>Technical &amp; Chemical Specifications<\/strong><\/p>\n<ul>\n<li><strong>Classification:<\/strong> Multi-Peptide Research Complex<\/li>\n<li><strong>Blend Composition:<\/strong> BPC-157 + TB-500 + GHK-Cu<\/li>\n<li><strong>Form:<\/strong> Sterile lyophilized blue powder (cake)<\/li>\n<li><strong>Component Identification:<\/strong> Verified via Mass Spectrometry (MS) and analytical HPLC<\/li>\n<li><strong>Recommended Reconstitution Solvent:<\/strong> Sterile bacteriostatic water or sterile deionized laboratory water (avoid phosphate buffers due to the presence of GHK-Cu and the risk of insoluble copper phosphate precipitation)<\/li>\n<li><strong>Storage Conditions:<\/strong> Store long-term at -20 \u00b0C in a dry, dark environment. Following reconstitution, keep refrigerated at 2\u20138 \u00b0C and utilize within standard experimental protocol timelines.<\/li>\n<\/ul>\n<p><strong>Scientific References &amp; Literature<\/strong><\/p>\n<ul>\n<li><i>Sikiric, P., et al.<\/i> Stable gastric pentadecapeptide BPC 157: In vitro and in vivo mechanisms in cellular protection and angiogenesis. <i>Current Pharmaceutical Design<\/i>, 2018.<\/li>\n<li><i>Goldstein, A. L., et al.<\/i> Thymosin beta 4: Actin-sequestering protein and its multifaceted roles in cellular motility and tissue repair. <i>Annals of the New York Academy of Sciences<\/i>, 2007.<\/li>\n<li><i>Pickart, L., et al.<\/i> Regenerative and protective actions of the GHK-Cu peptide in light of the new gene data. <i>International Journal of Molecular Sciences<\/i>, 2018.<\/li>\n<li><i>Gospodarowicz, D., et al.<\/i> Synergistic effects of cellular growth factors and matrix-associated peptides on fibroblast and endothelial proliferation in vitro. <i>Journal of Cellular Physiology<\/i>, 1995.<\/li>\n<\/ul>\n<p><strong>Legal Disclaimer &amp; Terms of Purchase<\/strong><\/p>\n<p>This product is classified and supplied <strong>strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only \u2013 RUO)<\/strong>. This compound is not a drug, medicine, dietary supplement, cosmetic product, or substance intended for human or veterinary consumption, direct administration, injection, or diagnostic procedures.<\/p>\n<p>By placing an order, the purchaser explicitly confirms that they are <strong>at least 18 years of age<\/strong>, possess the requisite professional qualifications and laboratory equipment to safely handle research materials, and are fully conversant with all relevant safety protocols for managing research substances. The seller assumes no liability for any use contrary to these terms.<\/p>\n","protected":false},"excerpt":{"rendered":"<ul>\n<li><strong>Intended Use:<\/strong> This product is supplied <strong>strictly for laboratory, scientific, and research purposes only (Research Use Only \/ in vitro)<\/strong>. It is not a medicinal product, food, or dietary supplement. The substance is not intended for human or animal consumption, administration, or therapeutic use.<\/li>\n<li><strong>Form &amp; Contents:<\/strong> Supplied as a sterile lyophilized powder in a sealed laboratory vial. Does not include reconstitution solvent unless explicitly stated.<\/li>\n<li><strong>Recommended Storage:<\/strong> To maintain maximum stability, store the unopened vial in a cool, dry, and dark place at 2\u20138 \u00b0C (recommended at -20 \u00b0C for long-term storage).<\/li>\n<li><strong>Illustrative Product Image:<\/strong> Product images are for <strong>illustrative purposes only<\/strong>. The actual appearance of the vial, flip-off cap color, or laboratory label design may vary depending on the production batch.<\/li>\n<\/ul>\n","protected":false},"featured_media":1889,"template":"","meta":[],"product_brand":[],"product_cat":[47],"product_tag":[],"class_list":["post-1888","product","type-product","status-publish","has-post-thumbnail","product_cat-lyophilized-compounds","first","instock","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>GLOW 70mg - Nextrabiochem.eu<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GLOW 70mg - Nextrabiochem.eu\" \/>\n<meta property=\"og:description\" content=\"Intended Use: This product is supplied strictly for laboratory, scientific, and research purposes only (Research Use Only \/ in vitro). 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