{"id":1957,"date":"2026-09-11T08:15:52","date_gmt":"2026-09-11T08:15:52","guid":{"rendered":"https:\/\/nextrabiochem.eu\/produkt\/l-carnitine-600mg\/"},"modified":"2026-09-11T12:16:05","modified_gmt":"2026-09-11T12:16:05","slug":"l-carnitine-600mg","status":"publish","type":"product","link":"https:\/\/nextrabiochem.eu\/en\/produkt\/l-carnitine-600mg\/","title":{"rendered":"L Carnitine 600mg"},"content":{"rendered":"<p><strong>L-Carnitine 600 mg \/ ml \u2013 In Vitro Research Solution (600 mg \/ ml)<\/strong><\/p>\n<p><i>Pure biologically active L-carnitine in an optimized sterile solution for in vitro research on fatty acid mitochondrial transport, <\/i>\u03b2<i>-oxidation activation, cellular energy metabolism modulation, and oxidative capacity in cellular models<\/i><\/p>\n<p><strong>Overview &amp; Mechanism of Action (In Vitro)<\/strong><\/p>\n<p><strong>L-Carnitine<\/strong> (a quaternary ammonium compound of \u03b2-hydroxy-\u03b3-trimethylaminobutyric acid) is a vital endogenous cofactor essential for intracellular fatty acid transport across stereoisomeric D- and L-specifications. In cellular biology, metabolic biochemistry, and energy homeostasis research, it serves as a primary reference standard for investigating lipid metabolism and mitochondrial bioenergetics:<\/p>\n<ul>\n<li><strong>Regulation of Fatty Acid Mitochondrial Transport:<\/strong> Acts as an essential substrate for carnitine palmitoyltransferase enzymes (CPT-I and CPT-II), thereby mediating the translocation of long-chain fatty acids across the inner mitochondrial membrane for subsequent \u03b2-oxidation in vitro.<\/li>\n<li><strong>Modulation of the Acyl-CoA\/CoA Ratio:<\/strong> Regulates intracellular free coenzyme A levels, maintaining optimal conditions for the activity of key Krebs cycle enzymes and oxidative phosphorylation within cell cultures.<\/li>\n<li><strong>Antioxidant &amp; Neuroprotective Effects in Cellular Models:<\/strong> In primary cultures and cell lines, it exhibits the capacity to scavenge reactive oxygen species (ROS), protect cell membranes against lipid peroxidation, and support mitochondrial membrane potential stability under stress stimuli.<\/li>\n<li><strong>Support of Cellular Viability &amp; Energy Plasticity:<\/strong> Contributes to sustaining optimal ATP production and minimizing the accumulation of intermediate toxic acyl-CoA metabolites across myogenic and hepatic cell lines in vitro.<\/li>\n<li><strong>Pre-formulated Format for Precise Laboratory Dispensing:<\/strong> A stabilized 600 mg\/ml solution eliminates the need for manual weighing of hygroscopic powders, ensuring immediate biological availability in media and high reproducibility during micro-dispensing.<\/li>\n<\/ul>\n<p><strong>Technical &amp; Chemical Specifications<\/strong><\/p>\n<ul>\n<li><strong>Classification:<\/strong> Mitochondrial Fatty Acid Transporter \/ Metabolic Regulator \/ Research Solution (RUO)<\/li>\n<li><strong>Product Form:<\/strong> Sterile stabilized clear solution \/ Ready-to-Use (RTU)<\/li>\n<li><strong>Compound Concentration:<\/strong> 600 mg \/ ml (high-capacity laboratory standard)<\/li>\n<li><strong>Chemical Name:<\/strong> (3R)-3-hydroxy-4-(trimethylammonio)butanoate<\/li>\n<li><strong>Molecular Formula:<\/strong> C7H15NO3<\/li>\n<li><strong>Molecular Weight:<\/strong> 161.20\u00a0g\/mol<\/li>\n<li><strong>Solution Matrix:<\/strong> Sterile buffered aqueous matrix for laboratory use (pH-optimized, free of preservatives that interfere with cell cultures)<\/li>\n<li><strong>Storage Conditions:<\/strong> Store at 2\u20138 \u00b0C in a dark, refrigerated environment. Protect from freezing and direct sunlight. Maintain standard laboratory cold-chain protocols.<\/li>\n<\/ul>\n<p><strong>Scientific References &amp; Literature<\/strong><\/p>\n<ul>\n<li><i>Bremer, J.<\/i> Carnitine\u2014metabolism and functions: In vitro kinetics and transport mechanisms in cellular systems. <i>Physiological Reviews<\/i>, 1983.<\/li>\n<li><i>Pande, S. V.<\/i> Role of carnitine in acyl group transfer inside mitochondria in cellular models. <i>Journal of Biological Chemistry<\/i>, 1975.<\/li>\n<li><i>Vaz, F. M., &amp; Wanders, R. J.<\/i> Carnitine biosynthesis in mammals: Biochemistry, transport, and in vitro evaluation. <i>Biochemical Journal<\/i>, 2002.<\/li>\n<li><i>Ringseis, R., et al.<\/i> Mechanisms of action of L-carnitine on lipid metabolism and mitochondrial function in cell cultures. <i>Pharmacological Research<\/i>, 2012.<\/li>\n<\/ul>\n<p><strong>Legal Disclaimer &amp; Terms of Purchase<\/strong><\/p>\n<p>This product is classified and supplied <strong>strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only \u2013 RUO)<\/strong>. The stabilized solution is not a drug, medicine, fat burner, dietary supplement, energy tonic, or medical device, and is not intended for human or veterinary consumption, oral ingestion, direct administration, injection, or diagnostic procedures.<\/p>\n<p>By placing an order, the purchaser explicitly confirms that they are <strong>at least 18 years of age<\/strong>, possess the requisite professional qualifications and laboratory infrastructure to safely handle research substances, and are fully conversant with all relevant laboratory safety protocols. The seller assumes no liability for any use contrary to these terms.<\/p>\n","protected":false},"excerpt":{"rendered":"<ul>\n<li><strong>Intended Use:<\/strong> This product is supplied <strong>strictly for laboratory, scientific, and research purposes only (Research Use Only \/ in vitro)<\/strong>. It is not a medicinal product, food, or dietary supplement. The substance is not intended for human or animal consumption, administration, or therapeutic use.<\/li>\n<li><strong>Form &amp; Contents:<\/strong> Supplied as a sterile lyophilized powder in a sealed laboratory vial. Does not include reconstitution solvent unless explicitly stated.<\/li>\n<li><strong>Recommended Storage:<\/strong> To maintain maximum stability, store the unopened vial in a cool, dry, and dark place at 2\u20138 \u00b0C (recommended at -20 \u00b0C for long-term storage).<\/li>\n<li><strong>Illustrative Product Image:<\/strong> Product images are for <strong>illustrative purposes only<\/strong>. The actual appearance of the vial, flip-off cap color, or laboratory label design may vary depending on the production batch.<\/li>\n<\/ul>\n","protected":false},"featured_media":1958,"template":"","meta":[],"product_brand":[],"product_cat":[47],"product_tag":[],"class_list":["post-1957","product","type-product","status-publish","has-post-thumbnail","product_cat-lyophilized-compounds","first","instock","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L Carnitine 600mg - Nextrabiochem.eu<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L Carnitine 600mg - Nextrabiochem.eu\" \/>\n<meta property=\"og:description\" content=\"Intended Use: This product is supplied strictly for laboratory, scientific, and research purposes only (Research Use Only \/ in vitro). 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