Description

GLOW (GHK-Cu 50 mg + BPC-157 10 mg + TB-500 10 mg) – Pre-filled Laboratory Cartridge for In Vitro Research (70 mg / 3 ml)

Multi-component synergistic research peptide complex comprising copper tripeptide (GHK-Cu), gastric pentadecapeptide (BPC-157), and biomimetic thymosin  fragment (TB-500) in a pre-formulated stabilized buffered solution for in vitro research on multi-target extracellular matrix remodeling, angiogenesis, actin cytoskeleton dynamics, and cytoprotection

Overview & Mechanism of Action (In Vitro)

The GLOW research complex is a triple-peptide bioactive formulation engineered for comparative and combinatorial in vitro investigation across cell biology, regenerative matrix biochemistry, and experimental tissue engineering:

• Triple-Action Extracellular Matrix (ECM) Synthesis: GHK-Cu upregulates gene transcription of type I and III collagen and tropoelastin, BPC-157 accelerates fibroblast migration and structural matrix deposition via FAK-paxillin focal adhesion cascades, and TB-500 coordinates matrix remodeling in vitro.
• Complementary Angiogenic Pathways & Microvascular Organization: BPC-157 promotes VEGFR2 phosphorylation and eNOS activation, TB-500 facilitates endothelial tube formation through matrix metalloproteinase (MMP) modulation, and GHK-Cu enhances basic fibroblast growth factor (bFGF) and VEGF secretion in vitro.
• Actin Cytoskeletal Dynamics & Motility Optimization: TB-500 sequesters monomeric G-actin in a 1:1 ratio to preserve cytoskeletal remodeling capacity, while BPC-157 coordinates focal adhesion kinase assembly, accelerating wound closure in monolayer scratch assays.
• Comprehensive Cytoprotection & Antioxidant Signaling: Synergistically enhances superoxide dismutase (SOD) activity, suppresses caspase-3 cleavage, and activates the Akt pathway, protecting cell cultures against oxidative and hypoxic stress in vitro.
• Pre-formulated Format for Precise Laboratory Dispensing: A stable liquid formulation containing all three peptides at a defined 5:1:1 ratio (70 mg total active peptide content / 3 ml) eliminates errors associated with separate manual reconstitution and blending steps.

Technical & Chemical Specifications

• Classification: Multi-Component Peptide Standard / Extracellular Matrix Modulator / Research Peptide Solution (RUO)
• Product Format: Pre-filled calibrated laboratory cartridge (3 ml volume)
• Active Content per Cartridge (Total 70 mg / 3 ml):
  • GHK-Cu: 50 mg (approx. 16.67 mg/ml concentration)
  • BPC-157: 10 mg (approx. 3.33 mg/ml concentration)
  • TB-500: 10 mg (approx. 3.33 mg/ml concentration)
  • Total Peptide Strength: approx. 23.33 mg/ml
• Form: Sterile stabilized characteristic blue solution / Ready-to-Use (RTU)
• Solution Matrix: Sterile buffered isotonic solution for laboratory use (pH-optimized, requires no reconstitution or dilution)
• Compatibility: Compatible with standard laboratory dispensing pens and micro-dispensers for 3 ml cartridges (dispensing pen/injector is not included in the package)
• Storage Conditions: Store at 2–8 °C in a dark, refrigerated environment. Do not freeze. Maintain standard laboratory cold-chain protocols to preserve compound stability.

Scientific References & Literature

• Pickart, L., & Margolina, A. Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 2018.
• Sikiric, P., et al. Stable gastric pentadecapeptide BPC 157 in cellular systems: In vitro mechanisms of endothelial survival, VEGF upregulation, and tissue remodeling. Current Pharmaceutical Design, 2018.
• Goldstein, A. L., et al. Thymosin beta4: Actin-sequestering protein and its multifunctional role in cellular migration and tissue repair in vitro. Annals of the New York Academy of Sciences, 2012.
• Philp, D., et al. The actin-binding site on thymosin beta4 promotes angiogenesis and wound repair in cellular models. FASEB Journal, 2003.

Legal Disclaimer & Terms of Purchase

This product is classified and supplied strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only – RUO). The stabilized peptide solution and mechanical cartridge are not drugs, medicines, cosmetic formulations, anti-aging agents, dietary supplements, or medical devices, and are not intended for human or veterinary consumption, oral ingestion, direct administration, injection, or diagnostic procedures.

By placing an order, the purchaser explicitly confirms that they are at least 18 years of age, possess the requisite professional qualifications and laboratory infrastructure to safely handle research substances, and are fully conversant with all relevant laboratory safety protocols. The seller assumes no liability for any use contrary to these terms.