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BPC-157 + TB-500 Capsules

BPC-157 + TB-500 Capsules

75,90 €

  • Intended Use: This product is supplied strictly for laboratory, scientific, and research purposes only (Research Use Only / in vitro). It is not a medicinal product, food, or dietary supplement. The compound in a solid carrier is not intended for application, consumption, or any therapeutic use in humans or animals.
  • Form & Presentation: Contains precisely pre-weighed research material within an enclosed capsule carrier for convenient laboratory handling.
  • Recommended Storage: Store in the original sealed container in a cool, dry, and dark place at temperatures up to 20 °C. Protect from moisture and direct sunlight.
  • Illustrative Product Image: Product images are for illustrative purposes only. Capsule coloration, packaging format, or laboratory label design may vary depending on the production batch.
Product code: BB1000 Category:

10 in stock

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Description

BPC-157 + TB-500 – Research Capsules for Laboratory Purposes (500 mcg + 500 mcg / capsule, 60 count)

Dual synthetic bioactive peptide complex in a solid analytical matrix for in vitro research on synergistic cell migration, G-actin dynamics, FAK-paxillin pathway activation, angiogenesis, collagen synthesis, and cytoprotection

Overview & Mechanism of Action (In Vitro)

BPC-157 + TB-500 is a coordinated dual-peptide research system combining two complementary bioactive entities: the stable gastric pentadecapeptide (BPC-157) and the synthetic functional domain of Thymosin Beta-4 (TB-500). In cellular biology, regenerative tissue engineering, and experimental molecular physiology, this dual complex serves as a primary model for studying synergistic molecular interactions involved in cytoskeletal organization, extracellular matrix deposition, and cellular integrity. Encapsulation into a standardized solid matrix ensures chemical stability for both peptide components, protection against ambient humidity, and precise aliquot dispensing for laboratory assays:

  • Synergistic Cell Motility & Directed Migration: The simultaneous modulation of actin cytoskeletal plasticity via G-actin sequestration (TB-500) and focal adhesion kinase (FAK-paxillin) activation (BPC-157) accelerates directional migration in fibroblast, myoblast, and endothelial cell cultures during in vitro wound closure assays.
  • Complementary Angiogenic & Vascular Organization: Combines VEGFR2 receptor upregulation (BPC-157) with endothelial capillary tube assembly (TB-500) in primary vascular cell models.
  • Extracellular Matrix Remodeling & Type I Collagen Deposition: BPC-157 enhances transcriptional collagen synthesis, while TB-500 provides the necessary cytoskeletal scaffolding for structured fiber alignment.
  • Downregulation of Inflammatory Cascades & ROS Control: Suppresses nuclear translocation of NF-κB and limits pro-inflammatory mediator release (TNF-α, IL-6) while stabilizing eNOS activity and reducing intracellular reactive oxygen species (ROS) accumulation.

Technical & Chemical Specifications

  • Classification: Dual Research Peptide Complex in Solid Matrix / Reagent Analytical Capsules (RUO)
  • Active Content per Capsule: BPC-157 (500 mcg / 0.5 mg) + TB-500 (500 mcg / 0.5 mg) (±2%)
  • Packaging Unit: 60 research capsules in a laboratory container with integrated desiccant
  • Form: Solid reagent matrix / encapsulated powder standard
  • Component Identification: Both active components independently verified via Analytical HPLC and Mass Spectrometry (MS)
  • Recommended Reconstitution Protocol: Capsule contents are intended for dissolution in sterile laboratory buffers (e.g., sterile PBS pH 7.2–7.4) or sterile water to prepare calibrated working solutions for in vitro assays.
  • Storage Conditions: Store at 15–25 °C in a dry, dark environment in the tightly sealed original container with desiccant. For long-term archiving of analytical standards, storage at -20 °C is recommended.

Scientific References & Literature

  • Sikiric, P., et al. Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157 and cellular pathways of tissue repair. Current Medicinal Chemistry, 2012.
  • Goldstein, A. L., et al. Thymosin beta4: Actin-sequestering protein and its multifunctional role in tissue repair and regeneration. Expert Opinion on Biological Therapy, 2012.
  • Chang, C. H., et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 2011.
  • Philp, D., et al. Thymosin beta4 promotes cell migration, angiogenesis, and accelerates dermal wound healing in vitro and in vivo. Journal of Cellular Biochemistry, 2004.

Legal Disclaimer & Terms of Purchase

This product is classified and supplied strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only – RUO). Neither the compound nor the capsule matrix is a drug, medicine, dietary supplement, cosmetic product, or substance intended for human or veterinary consumption, oral ingestion, direct administration, injection, or diagnostic procedures.

By placing an order, the purchaser explicitly confirms that they are at least 18 years of age, possess the requisite professional qualifications and laboratory equipment to safely handle research materials, and are fully conversant with all relevant safety protocols for managing research substances. The seller assumes no liability for any use contrary to these terms.

Legal Disclaimer & Terms of Purchase

This product is classified and supplied strictly for laboratory, scientific, and in vitro research purposes only (Research Use Only – RUO). Neither the compound nor the capsule matrix is a drug, medicine, dietary supplement, cosmetic product, or substance intended for human or veterinary consumption, oral ingestion, direct administration, injection, or diagnostic procedures.

By placing an order, the purchaser explicitly confirms that they are at least 18 years of age, possess the requisite professional qualifications and laboratory equipment to safely handle research materials, and are fully conversant with all relevant safety protocols for managing research substances. The seller assumes no liability for any use contrary to these terms.

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